Dinshaw J Patel

Latest

• Binding of guide piRNA triggers methylation of the unstructured N-terminal region of Aub leading to assembly of the piRNA amplification complex
• Cutoff suppresses RNA polymerase II termination to ensure expression of piRNA precursors
• Drosha and Dicer: Slicers cut from the same cloth
• Mouse MORC3 is a GHKL ATPase that localizes to H3K4me3 marked chromatin
• Structural basis for the unique multivalent readout of unmodified H3 tail by Arabidopsis ORC1b BAH-PHD cassette
• Structure and function of the bacterial decapping enzyme NudC
• Aub and Ago3 are recruited to nuage through two mechanisms to form a ping-pong complex assembled by Krimper
• TUT7 controls the fate of precursor microRNAs by using three different uridylation mechanisms
• Mechanism of DNA methylation-directed histone methylation by KRYPTONITE